The Effective Statistician - in association with PSI

The Effective Statistician - in association with PSI

The Effective Statistician - in association with PSI

Mistakes – How to minimize them – How to manage them

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Do you agree that everybody makes mistakes?
Have you had to deal with a mistake yourself, that you were really concerned about?
Were you afraid about speaking with your supervisor or your team with it?

We are all imperfect humans making mistakes. The questions are:

how do we deal with them,
what we can do about them, and
what to do to minimize them.

Processes are made to minimize mistakes and there different processes were set up to deal with mistakes and help you when mistakes occur.

Presenting with impact: 7 mistakes to avoid

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Have you been sitting in boring presentations that made you start reading your emails?
Have you been listening to someone, wondering if this is for me?
Have you been getting away from a presentation and thinking 2 hours later: “what was this about?”

You’re surely don’t want your audience to feel this way, when you’re presenting yourself. You can’t be an effective statisticians without good presentation skills from my perspective. You will always need to present results, defend designs, or explain data.

Todays episode will give you insights into 7 mistakes of presentations. And honestly, I see at least one of them in nearly every presentation and I struggle with them as well – just listen to this episode and you’ll have a live example 😊.

Join the abstract writing challenge!

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The last PSI conference has just ended, but the timeline for a new abstract submission for the next one in Barcelone in 2020 will come up in about November 2019. Thus, it’s important to now start thinking about it.

Presenting at the PSI conference is an awesome experience. For me, PSI is by far the best conference for statisticians in the health sector as it is 100% applicable and actionable. If you’re abstract gets accepted for oral presentation or as a poster, you have a great argument for convincing your supervisor to approve the travel to Barcelona.

If you think, this is to much of a stretch, because you’re not located in Europe, just think about a different conference.

Join the challenge to submit an abstract and work together with others to overcome and roadblocks!

Are you up for a job change? Insights from a recruiter

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I recently changed my job and moving from one company to another comes with lots of uncertainty.
Will I pick the right one?
How can I make sure, that I actually get the job, that I want?
Will hiring companies find me and offer me jobs?

For any statistician a job change represent a major shift and occurs rather infrequent – hopefully. For a recruiter – this is day-to-day business.

Look out for lots of great learnings and insights!

How to work effectively as and with a placement student

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Have you ever considered to work with a placement student?
Do you consider to spend some time as a placement student yourself?

In this interview with Katie Thorn and Claire Brittain, we’re exploring factors, which help to make it a win for both sides. Both have worked very well together and share their stories.

Questions to ask yourself before starting a new project

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I recently talked to a statistician, that initiated a small company internal group of statisticians to drive forward methodological innovation projects. While this surely will help the individuals to learn more about statistical methods, it was less clear, why and on which topics the group should focus their activities on.

While most of our day-to-day activities consists of running clinical studies, submissions and directly related work, we also engage in such innovation work streams or process improvement working groups and other such activities.

Today, we’re giving you advice on how to best pick the right projects to work on as you usually have some influence on this.

Understanding heterogeneity for patient preference data and how it effects the benefit-risk ratio for treatments

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As statisticians in the medical field, we’re used to study subgroups of patients with respect to all kinds of biological variables: from demographics to genomics. This provides us with a good understanding of how the benefit-risk profile for a given patient looks like.

However, the patient might have a completely different view on the importance of the different benefits and risks. And importantly, these preferences might be less driven by biologic factors and more by personal experiences and situations as well as psychological traits. How can we assess patient preferences in this regard?

Marco Boeri and I worked on such questions in the past and some work has been presented at last years PSI conference. In todays episode, we give you some insights into what’s possible and how you can approach this problem.

Useful tips to apply the composite estimand approach

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Estimands continue to be a hot topic, but many statisticians struggle to put it into practice. As statistician, we wonder about the correct interpretation and how to analyse different estimands.

In todays episode, we speak with Michael O’Kelly, an expert on this topic with lots of presentations around estimand (see e.g. the PSI events). He also won the award for Statistical Excellence in the Pharmaceutical Industry, jointly run by the RSS and Statisticians in the Pharmaceutical Industry (PSI).

Advanced approach for subgroup analyses in easy steps - SIDES

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One of the most common questions I got asked during my nearly 2 decades of being a statistician sounds similar to this: “Which patients have the best response to treatment?”
I’m sure, we all face this situation sooner or later and not surprisingly lots of research has happened in the last years on this area. In todays episode, we will help you to understand one of the best approaches I have come across to solve this problem in a rigorous yet sophisticated way: the SIDES approach.
Both Andy Nicholls and I have applied this approach in the past and we’ll use an example, which he presented during a PSI webinar.
Listen to this episode to learn step by step how to apply the SIDES method.

50 shades of pre-specification

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Prespecified=good and post-hoc=bad. This is how we as statistician see it usually and I did too. However, over the past years I realized more and more, that it’s not that easy.
How many details do you need to have to call an analysis pre-specified? Should we label a request to analyse a certain subgroup by regulators as well as a fishing expedition to find a significant subgroup both in the same way: post-hoc?
Lovisa and I together with some others are presenting at the next PSI conference about this topic and today, we dive already into this topic and identify different dimension to be considered to understand better the different shades pre-specified analyses.
Listen to this episode to avoid oversimplification and confusion in discussions in the future.

About this podcast

The podcast from statisticians for statisticians to have a bigger impact at work. This podcast is set up in association with PSI - Promoting Statistical Insight. This podcast helps you to grow your leadership skills, learn about ongoing discussions in the scientific community, build you knowledge about the health sector and be more efficient at work. This podcast helps statisticians at all levels with and without management experience. It is targeted towards the health, but lots of topics will be important for the wider data scientists community.

by Alexander Schacht and Benjamin Piske, biometricians, statisticians and leaders in the pharma industry

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